超声对肾综合征出血热肾动脉血流参数变化及血液流变学改变的对照分析

目的 观察肾综合征出血热(HFRS)患者肾内动脉血流动力学改变及血液流变学改变.方法 选取我院经实验室检查及临床确诊为HFRS的患者272例(HFRS组),经彩色多普勒超声仪检测患者肾内动脉的收缩期峰值血流速度(Vs)、舒张末期血流速度(Vd)和阻力指数(RI);检测血液流变学的8项指标.并与同期210例健康者(正常对...

Comparative analysis of hemodynamics and hemorheology changes of haemorrhagic fever with renal syndrome by ultrasonography

Objective To observe the hemodynamics and hemorheology changes in patients with haemorrhagic fever with renal syndrome （HFRS）. Methods Two hundred and seventy-two patients with HFRS confirmed by clinical and laboratorial examination were enrolled in this study. Their peak systolic velocity （ Vs ） , end diastolic velocity （ Vd ） and resistance index （RI） of the renal artery were measured by color Doppler flow imaging （CDFI）, and hemorheology parameters were measured. The parameters of 210 healthy subjects （control group）were measured too, their results were compared and analyzed. Results There was no significant difference of CDFI parameters between two groups at fervescence stage （ P 〉 O. 05）, while the whole blood viscosity, polycythaemia compress volume in HFRS group were lower than those in control group （P 〈 0.05 ）, the Vd, Vs in HFRS group were lower and the RI was higher than that in control group at the stages of hypotensive shock and anuria （ P 〈 0.05 ） , obvious changes were also observed in hemorheology test. In diuresis stage, Vs and Vd were increased, but they are still lower than those in control group. RI was similar to that in control group. The hemorheology parameters returned to normal levels except the fibrinogen, blood sedimentation and erythrocyte sedimentation rate equation K＇ s value. In recovery stage, all hemodynamics and hemorheology parameters returned to normal levels. Conclusion The parameters of hemodynamics and hemorheology in various stages of HFRS have certain regularity. There is specific diagnostic value of color Doppler ultrasound in examining hemodynamic changes, and it can reflect the state of renal blood flow.