后凸成形中骨水泥量对相邻椎体终板影响的有限元分析

背景：最近研究表明经皮椎体后凸成形后存在相邻椎体骨折的问题，推测骨水泥泄露可能是其中的重要原因。 目的：探讨经皮椎体后凸成形中骨水泥量对相邻椎体终板的生物力学影响。 方法：建立骨质疏松性椎体压缩骨折病理三维有限元模型，分别在骨折椎体内填充10%，20%和30%椎体容积的骨水泥，分析轴向压缩、前屈和后伸三种情况下相邻椎体终板应力的变化情况。 结果与结论：与填充前相比，骨水泥容积按10%，20%和30%填充后，相邻椎体终板各种情况下的应力均增加，且随着骨水泥填充容积增加而增加。说明经皮椎体后凸成形中骨水泥用量增加，会导致相邻椎体骨折增加的概率。 中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

Effect of bone cement amount on adjacent vertebral endplate during percutaneous kyphoplasty: a finite element analysis

BACKGROUND:Recent studies have proved the presence of adjacent vertebral fractures after percutaneous kyphoplasty, suggesting that cement leakage may be an important reason. OBJECTIVE: To investigate the effect of bone cement amount during percutaneous kyphoplasty on adjacent vertebral endplate using finite element analysis. METHODS:Three-dimensional finite element pathological model of Osteoporotic vertebral compression fracture was established using finite element analysis, and 10%, 20% and 30% volume of bone cement were filled, respectively. Then the adjacent vertebral endplate stress under the axial compression, anteflexion and rear protraction were analyzed. RESULTS AND CONCLUSION:Compared with that before operation, the adjacent vertebral endplate stress increased with the increase in filled bone cement volume, suggesting that the increased amount of bone cement will lead to the increasing of adjacent vertebral re-fractures.