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骨水泥加固椎弓根螺钉的生物力学特性
作者姓名:隆海滨  孙桂森  王卫国
作者单位:胜利油田中心医院脊柱外科,山东省东营市 257034;中南大学湘雅三医院骨科,湖南省长沙市 410015
摘    要:背景:由于骨质原因及结构特点导致椎弓根螺钉经常出现把持力下降,从而发生松动、拔出,导致内固定失败,因此提高椎弓根螺钉的稳定性显得尤为重要。 目的:检测可注射骨水泥空心椎弓根螺钉椎弓根螺钉生物力学稳定性,为优化骨水泥使用量提供参考。 方法:选取7具新鲜成人尸体T11-L4椎体标本共40个椎体,随机分为可注射骨水泥空心椎弓根螺钉及DTPSTM椎弓根螺钉组,各20个,置钉后分别注入1,2,3,5 mL骨水泥,通过影像学观察骨水泥弥散分布情况,并测得最大轴向拔出力进行比较。 结果与结论:骨水泥用量为1-3 mL时,可注射骨水泥空心椎弓根螺钉组螺钉平均最大轴向拔出力显著高于DTPSTM组(P < 0.05)。骨水泥用量为5 mL时,2组平均最大轴向拔出力差异无显著性意义(P > 0.05)。可注射骨水泥空心椎弓根螺钉组的直线回归方程为Y=25.269X+133.681(R2=0.837),DTPSTM椎弓根螺钉组的直线回归方程为Y=32.039X+99.251(R2=0.936)。骨水泥用量在1-5 mL时,2组螺钉最大轴向拔出力与骨水泥量高度正相关(|R| > 0.8)。说明骨水泥强化椎弓根螺钉可显著提高螺钉稳定性,椎弓根螺钉最大轴向拔出力与骨水泥使用量呈高度正相关,可注射骨水泥空心椎弓根螺钉在达到满意的内固定强化效果同时,减少骨水泥使用量,降低了骨水泥泄漏风险,相比DTPSTM椎弓根螺钉更具有优势。中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱;骨折;内固定;数字化骨科;组织工程

关 键 词:骨科植入物  脊柱植入物  骨水泥  椎弓根螺钉  生物力学  弥散分布  拔出力  把持力  三维重建  

Biomechanical properties of bone cement injectable canulated pedicle screw
Authors:Long Hai-bin  Sun Gui-sen  Wang Wei-guo
Institution:Spine Surgery, Shengli Oilfield Central Hospital, Dongying 257034, Shandong Province, China; Department of Orthopedics, the Third Xiangya Hospital of Central South University, Changsha 410015, Hunan Province, China
Abstract:BACKGROUND:Bony and structural feature often cause pullout strength decrease of pedicle screw, which induces loosening and pullout, and finally results in fixation failure. Thus, it is very important to elevate the stability of pedicle screw. OBJECTIVE:To detect the biomechanical stability of bone cement injectable canulated pedicle screw, and to provide reference for bone cement dosage.  METHODS:We selected T11-L4 samples of seven fresh adult corpses, containing 40 vertebral bodies. They were randomly divided into bone cement injectable canulated pedicle screw group and DTPSTM pedicle screw group (n=20). After screw implantation, 1, 2, 3 and 5 mL bone cement was injected. The diffuse distribution of bone cement was observed by imaging. The maximum axial pullout strength was measured. RESULTS AND CONCLUSION:When the dose of bone cement was 1-3 mL, the average maximum axial pullout strength was significantly greater in the bone cement injectable canulated pedicle screw group than in the DTPSTM pedicle screw group (P < 0.05). When the bone cement dosage was 5 mL, no significant difference in the maximum axial pullout strength was detected between the two groups (P > 0.05). The regression equation was Y=25.269X+133.681 (R2=0.837) in the bone cement injectable canulated pedicle screw, and Y=32.039X+99.251 (R2=0.936) in the DTPSTM pedicle screw group. When the dosage of bone cement was 1-5 mL, the maximum axial pullout strength was highly positively correlated with bone cement dosage (|R| > 0.8). These results suggested that bone cement augmentation pedicle screw could apparently elevate the stability of the screw. The maximum axial pullout strength of the pedicle screw was positively correlated with bone cement dosage. After reaching the satisfactory fixation effects, the bone cement injectable canulated pedicle screw can reduce bone cement dosage, diminish the risk of bone cement leakage, and have more advantages than DTPSTM pedicle screw.
Keywords:Bone Nails  Bone Remodeling  Biomechanics  Bioprosthesis  
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