Pregnancy and uncomplicated vaginal delivery only 13 months after cardiac transplantation (case report) |
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Authors: | A Zuckermann MD M Grimm Regine Ahner Paul Simon Peter Buxbaum G Laufer E Wolner |
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Institution: | 1. Division of Cardiothoracic Surgery, Department of Surgery, University of Vienna, W?hringer Gürtel 18-20, A-1090, Vienna 2. the Department of Gynecology and Obstetrics I, University of Vienna, Vienna, Autria
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Abstract: | Summary
Background Pregnancy is prossible in female patients who underwent cardiac transplantation but is associated with unpredictable risks.
Methods A 23-year old female patient underwent cardiac transplantation because of dilatative cardiomyopathy.
Results Against our advice, she became pregnant 4 months after transplantation. Following an uneventful pregnancy, spontaneous vaginal
delivery occurred 13 months after transplantation. The patient gave birth to a healthy new-born in good physical condition.
Thereafter, the patient refused to attend any further routine follow-up control. 9 months after delivery, the patient was
admitted to hospital in severe cardiac shock. Biopsy showed a serious, acute rejection which was treated with a course of
methylprednisolone. Clinically, the patient recovered within 1 week, but died from acute myocardial infarction 1 day after
discharge from hospital.
Conclusions Only women without a history of rejection episodes, with good kidney function, good graft function, and high compliance should
be counselled to become pregnant.
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Keywords: | Pregnancy cardiac transplantation cyclosporine |
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