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Disturbed Liver Function in Migraine Patients
Authors:Ifor D. Capel  Ph.D.  M.I.  Biol.   Ellen C.G. Grant  M.B.  Ch.B.  D. Obst. R.C.O.G.   Helen M. Dorrell  Marisa H. Pinnock  L.I. Biol.   F. Clifford Rose  F.R.C.P.   Donald C. Williams  Ph.D.  F.R.I.C.
Affiliation:From the Research Department, Marie Curie Memorial Foundation, The Chart, Oxted, Surrey, England; Neurology Department, Charing Cross Hospital, Fulham Palace Road, London, England
Abstract:SYNOPSIS
Hepatic function as estimated from the plasma kinetics of antipyrine has been determined in 32 migraine patients. A high proportion of patients exhibited abnormal plasma half-life and metabolic clearance rates for this drug. The serum levels of copper and zinc were also estimated in these patients; the ratio copper:zinc was uniformly higher than that of controls.
Keywords:
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