盐酸替罗非班对急诊经皮冠状动脉介入治疗无再流现象的影响

目的：观察盐酸替罗非班对ST段抬高急性心肌梗塞（STEMI）患者急诊经皮冠状动脉介入治疗（PCD中血流的影响。方法：一选择急诊入院STEMI患者43名，随机分为盐酸替罗非班组23例和对照组20例。替罗非班组PCI术前开始应用盐酸替罗非班，持续泵人至术后36-48h。对照组应用常规PCI。收集所有病例的临床及冠状动脉造影资料，观察PCI术前、术后血流情况。结果：替罗非班组急诊PCI术后TIMI血流3级的发生率（94％）较对照组（89％）显著增加（P〈0．05）。结论：替罗非班可改善STEMI患好梗塞相关血管的TIMI血流。

Effects of tirofiban on no-reflow in patients with acute myocardial infarction during emergency percutaneous coronary intervention

Objective: To investigate the effects of tirofiban on no-reflow in patients with ST segment elevation acute myocardial infarction(STEMI) during emergency percutaneous coronary intervention(PCI).Methods: Forty-three patients with STEMI who underwent emergency PCI were randomly divided into tirofiban group(n=23) and control group(n=20).Tirofiban was used in the former group before operation and continued for 36~48 h after PCI.In the latter group,PCI was performed through routine process.The TIMI flow before and after the operation was reviewed by angiography.Results:Ninety-four percent patients in the tirofiban group were recovered with TIM 3 grade flow;it was more than that in the control group(89%),P<0.05.Conclusion:Tirofiban may improve TIMI flow in patients with STEMI during emergency PCl.