| 脑胶质瘤术后125I粒子永久植入近距离内放疗的临床应用与观察 |
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| 引用本文： | 马骏,耿晓增,程刚,陈海峰,傅震.脑胶质瘤术后125I粒子永久植入近距离内放疗的临床应用与观察[J].临床神经外科杂志,2007,4(2):55-57. |
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| 作者姓名： | 马骏 耿晓增 程刚 陈海峰 傅震 |
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| 作者单位： | 210029,南京医科大学;南京医科大学第一附属医院神经外科 |
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| 摘 要： | 目的探讨配合手术治疗进行^125I粒子永久植入近距离放疗治疗脑胶质瘤的临床疗效及操作方法。方法11例脑胶质瘤患者在手术治疗同时结合CT、术中及直视下进行^125I粒子植入治疗,肿瘤匹配剂量90～110Gy,每颗粒子剂量0.7mCi,每例患者植入粒子数8～10颗。结果随访一年,死亡2例,存活9例,9例患者卡氏评分较治疗前有提高,随访期内,无严重并发症。结论此技术适应证广,安全有效,为恶性脑胶质瘤的综合治疗增添了新的手段。
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| 关 键 词： | 脑胶质瘤 近距离疗法 125I放射性粒子 |
| 文章编号： | 1672-7770（2007）02-0055-03 |
| 修稿时间： | 2006-11-102006-12-06 |
Clinical study of brachytherapy with Iodine-125 for gliomas |
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| MA Jun, GENG Xiao-zeng, CHEN Gang,et al..Clinical study of brachytherapy with Iodine-125 for gliomas[J].Journal of Clinical Neurosurgery,2007,4(2):55-57. |
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| Authors: | MA Jun GENG Xiao-zeng CHEN Gang |
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| Institution: | Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University,Nanjing 210029, China |
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| Abstract: | Objective To study the clinical efficacy of brachytherapy with Iodine-125 for gliomas. Methods From October 2005 to October 2006,11 patients were treated by the implantation of ^125I radionuclide. Results Over one year survival in 9 cases, no acute or chronic radiation side effect were observed in the follow-up. Conclusions The implanting of ^125I radionuclide can evidently improve the quality of life and prolong survival time. It is an effective method for the treatment of gliomas. |
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| Keywords: | glioma iiradiation therapy brachytherapy Iodine-125 |
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