| E-cadherin and β-catenin expression in pancreatic intraepithelial neoplasia and pancreatic adenocarcinoma |
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| 作者姓名： | 郑建明 朱明华 倪灿荣 于观贞 王炜 林万和 龚志锦 |
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| 作者单位： | Department of Pathology，Changhai Hospital，Second Military Medical University，Shanghai 200433，China，Department of Pathology，Changhai Hospital，Second Military Medical University，Shanghai 200433，China，Department of Pathology，Changhai Hospital，Second Military Medical University，Shanghai 200433，China，Department of Pathology，Changhai Hospital，Second Military Medical University，Shanghai 200433，China，Department of Pathology，Changhai Hospital，Second Military Medical University，Shanghai 200433，China，Department of Pathology，Changhai Hospital，Second Military Medical University，Shanghai 200433，China，Department of Pathology，Changhai Hospital，Second Military Medical University，Shanghai 200433，China |
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| 基金项目： | Supported by Changhai Hospital Subject ConstructProgram. |
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| 摘 要： | Epithelial- cadherin (E- cad) is an importantmediator of maintaining epithelial integrity andintercellular adhesion.Aberrant expression anddysfunction of E- cad are reported to be implicated inthe invasion and metastasis of numerous malignantepithelial tumors[1,2 ] .β- catenin (β- cat) ,a multi-functional protein,is able to combine with E- cad toform complex- mediated cell- cell homotypicadhesion,and on the other hand,β- cat as a keymember in the Wnt- signaling pathway participatesin the r…
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| 关 键 词： | 胰腺上皮瘤 胰腺癌 E-钙粘素 基因表达 |
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