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经肝动脉灌注90Y微球治疗肝癌的研究进展
引用本文:周云,刘璐,宋进华. 经肝动脉灌注90Y微球治疗肝癌的研究进展[J]. 国际放射医学核医学杂志, 2006, 30(6): 321-324
作者姓名:周云  刘璐  宋进华
作者单位:210009,南京,东南大学核医学技术研究所;210006,南京医科大学附属南京第一医院放射介入科
基金项目:国家自然科学基金资助项目(30470500)
摘    要:近年来,肿瘤核素内照射治疗的研究取得了很大的进展。~(90)Y被视为绿色无公害核素备受关注。~(90)Y玻璃微球通过肝动脉给药,可以发挥栓塞肿瘤供血动脉和内照射治疗肿瘤的双重作用,具有操作简单、适应证广泛、不良反应少及肿瘤响应明显等优点,有效地提高了患者的生存率和中位生存期。随着微球材料技术的进一步发展,~(90)Y徽球肝动脉灌注可能成为治疗肝癌患者安全有效、具有广阔临床应用前景的新方法。

关 键 词:  肝细胞  钇放射性同位素  放射学  介入性  栓塞  治疗性
文章编号:1673-4114(2006)06-0321-04
修稿时间:2006-04-23

Clinical researched progress of intra-arterial radioembolization with 90Y-glass microspheres for treatment of hepatocellular carcinoma
ZHOU Yun,LIU Lu,SONG Jin-hua. Clinical researched progress of intra-arterial radioembolization with 90Y-glass microspheres for treatment of hepatocellular carcinoma[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2006, 30(6): 321-324
Authors:ZHOU Yun  LIU Lu  SONG Jin-hua
Abstract:In recent years,the research of tumor nuclide internal radiation treatment has been carried out encouraging result.~(90)Y has been regarded green non-environmental damage nuclide.Intrahepatic arterial injection of ~(90)Y-glass microspheres perform dual function at embolism tumor blood supply artery and the internal radiation treatment tumor.It has many merits include simplified operation,wide-ranging indication,side effect few and the tumor response obvious.And the patient's survival rate and position lifetime has been effective enhanced.Along with the further development of microspheres material technique,this method will entirely possible to achieve a new effective and safe therapy for the patient and has extensively clinical foreground.
Keywords:Carcinoma  hepatocellular  Yttrium radioisotopas  Radiology  interventional  Embolization  therapeutic
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