维持性血液透析患者血压控制不良相关因素的Logistic回归分析

摘要:目的 探讨维持性血透患者血压控制不良的主要相关危险因素。方法 选择135例维持性血液透析患者为研究对象，根据血压控制情况分为血压控制正常组和血压控制不良组，观察并记录两组患者的年龄、性别、身体质量指数（BMI）、残肾尿量、促红细胞生成素剂量、透龄、透析间期体重变化、透析方式（是否定期行HDF）、KT/V值、是否达透析干体重、血中血红蛋白浓度等指标，进行单因素分析和非条件多因素Logistic回归分析。结果 单因素分析结果显示两组患者在BMI、透龄、透析间期体重是否增加3kg以上、是否定期行HDF、KT/V是否大于1.2、干体重是否达标、残肾尿量方面的差异有统计学意义。非条件多因素Logistic回归分析结果示未定期HDF、KT/V小于1.2、干体重不达标三个因素变量进入Logistic回归方程差异有统计学意义。结论 未定期行HDF、KT/V小于1.2、干体重不达标才是维持性血透患者高血压控制不良的主要相关危险因素。

Logistic regression analysis of Factors associated with poorly-controlled hypertension in maintenance hemodialysis patients

Abstract: [Objectives] To explore the primary risk factors associated with poorly-controlled hypertension in maintenance hemedialysis patients. [Methods] 135 maintenance hemedialysis cases were divided into well-controlled hypertension group(61cases)and poorly-controlled hypertension group(74 cases). BMI, urine volume of residual renal, erythropoietin dosage, time of maintenance hemodialysis, change of body weight during hemodialysis intermission, hemodialysis mode, KT/V values, dry body, hemachrome concentration were recorded. Singer-variable analysis and multi-variable Logistic regression analysis were performed to examine the risk factors associated with poorly-controlled hypertension. [Results] Singer-variable analysis showed that BMI, time of maintenance hemodialysis, body weight gain larger than 3kg during hemodialysis intermission, no regular HDF, KT／V value less than 1.2, no attaining dry body, urine volume of residual renal were significant different among two groups. Multi-variable Logistic regression analysis showed that no regular HDF,KT／V value less than 1.2, no attaining dry body were main risks to poorly-controlled hypertension. [Conclusion] no regular HDF, KT／V value less than 1.2, no attaining dry body were the primary risk factors associated with poorly-controlled hypertension.