妊娠肝内胆汁淤积症与胎儿窘迫关系的临床分析

目的探讨妊娠合并肝内胆汁淤积症（ICP）对胎儿宫内窘迫（包括胎儿出生前及出生时）的影响。方法 196例ICP孕妇（观察组）和同期其他2 812例孕妇（对照组）进行比较,包括胎儿宫内窘迫的发生、新生儿窒息（出生1 min Apgar评分反映宫内情况）。结果妊娠合并肝内胆汁淤积症对胎儿宫内窘迫的影响有显著的临床意义。结论严密监护ICP孕妇,适时终止妊娠,能够有效降低新生儿窒息、围生儿死亡的发生率,减少不良妊娠结局。剖宫产是目前终止ICP的重要手段。

Clinical analysis of the relationship between intrahepatic cholestasis of pregnancy and fetal distress

Objective To explore the effect of intrahepatic cholestasis of pregnancy on fetal distress.Methods 196 patients with ICP and 2812 normal controls were selected to be analyzed including fetal distress and neonatal anoxia.Results The incidence of fetal distress increased significantly with ICP.Conclusion Monitoring closely on gravida with ICP and termination of pregnancy timely can decrease the incidence of apnoea neonatorum and the rate of dead.The cesarean section is the most important method to prevent pre...