高血压病合并短暂性脑缺血发作患者血压变异性与颈动脉内膜中层厚度相关性研究

目的探讨血压变异性（BPV）和颈动脉内膜中层厚度（IMT）与高血压病患者短暂性脑缺血发作（TIA）发病的关系。方法收集我院神经内科2008年6月~2012年6月住院的合并TIA发作的高血压病患者84例为研究组,以同期住院的非合并脑卒中的高血压病患者84例为对照组,分别对两组患者做24h动态血压检查,计算24h平均收缩压（ASBP）、平均舒张压（ADBP）、收缩压变异性（SBPV）及舒张压变异性（DBPV）,同时检测两组患者的IMT。结果研究组和对照组在ASBP、ADBP差异无统计学意义（P〉0.05）;短暂性脑缺血发作组SBPV、DBPV和IMT均高于对照组,差异有统计学意义（P〈0.05）。结论短暂性脑缺血发作的发病与颈动脉内膜中层厚度及血压变异性具有相关性。

Association between blood pressure variability and carotid intima-media thickness in transient ischemic attack patients with hypertenion.

Objective To evaluate the association between blood pressure variability and carotid intima-media thickness in transient ischemic attack patients with hypertension.Methods We chosed 84 cases of patients with transient ischemic attack patients with hypertension in our hospital from Jun.2008 to Jun.2012,and 84 cases with hypertension as the control group.The 24-hour ambulatory blood pressure monitoring was performed in all patients.The ASBP,ADBP,SBPV and DBPV were calculated respectively.Cartiod intima-media thickness was measured with Doppler echocardiography.Results The ASBP,ADBP had no significant difference between the two groups（P〈0.05）,the SBPV,DBPV and IMT in TIA group were significantly higher than the control group（P〈0.05）.Conclusion Increased BPV and IMT were significantly associated with increased TIA with hypertension.