Effect of nicotine on rabbit blood platelet aggregation |
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| Authors: | K. Brinson B. K. Chakrabarti |
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| Affiliation: | Department of Surgery, St. Bartholomew's Hospital, London, Great Britain |
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| Abstract: | Nicotine did not induce platelet aggregation nor potentiate ADP-induced aggregation in rabbit citrated platelet-rich plasma, but did inhibit ADP-induced aggregation when added before ADP, and did reverse ADP-induced aggregation when added after ADP. In contrast to results obtained with human platelets, this latter effect of nicotine was not inhibited by adrenaline in rabbit platelets. |
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| Keywords: | ADP-induced aggregation Adrenaline Nictotine Rabbit platelets |
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