广西中枢神经系统疾病患者囊虫感染调查及流行病学分析

目的了解广西壮族自治区中枢神经系统（CNS）疾病患者中脑囊虫感染状况，分析其流行特征。方法用ELISA法检测2000-2008年来自治区疾控中心就诊的CNS疾病患者的囊虫特异性抗体，并对抗体阳性患者进行囊虫病流行病学分析。结果2736例CNS疾病患者血清和／或脑脊液中囊虫特异性抗体阳性者403人，阳性率为14．73％。阳性者分布于全自治区55个县（市、区），大多集中在广西南部的南宁市及周边的贵港、武呜、宾阳、横县等市县，在阳性者的构成比中，农村高于城市，男性多于女性，成人多于青少年，农民多于其他职业者；2000年以后检出的囊虫抗体阳性率整体呈逐渐下降的趋势．但流行的区域却逐渐扩大，尤其在交通、经济落后，环境卫生较差的边远山区。结论脑囊虫感染是引起广西人群CNS疾病的一个重要原因之一，在重点地区特定人群中开展囊虫病防治，是减少CNS疾病发生的重要手段。因此．今后在全自治区，尤其在边远山区仍需加强囊虫病防治工作。

Survey on Cysticercosis cellulosae infection in patients with center nerve system diseases and epidemiological analysis of Cysticercosis in Guangxi

Objective To understand the condition of Cysticercosis cellulosae infection in patients with center nerve system （CNS） diseases and to analyze the epidemical features in Guangxi. Methods Specific antibodies for Cysticercosis cellulosae in outpatients suffered with CNS diseases from 2000 to 2008 were detected by ELISA, and the positive cases were analyzed. Results TThe positive rate was 14.73% （403/2 736）. The positive cases distributed in 55 counties of Guangxi, mainly concentrated in Nanning City and the surrounding counties, Guigang, Wuming, Binyang, Hengxian, etc. For the positive cases, the cases in rural were more than in urban, the male was more than Female, the adult was more than teenager, and the farmer was more than other workers, The positive rate declined gradually from 2000, but the prevalence area expanded, especially in the remote inountainous region with undeveloped economic and poor sanitation. Conclusion Cysticercosis cellulosae infection was one of the ilnportai~t reasons for CNS diseases in Guangxi. It＇s an important means to reduce the incidence of CNS diseases by controlling cysticercosis in partictflar population in key areas. Therefore, we should strengthen the prevention of cysticercosis in Guangxi, especially in remote mountainous areas in the future.