化工人群糖尿病的危险因素调查

目的 探讨化工人群糖尿病的主要危险因素。方法 采用WHO(1999)诊断标准，对泸天化集团公司20岁以上的员工6387人，进行问卷调查、体格检查及血液生化指标测定，分析不同因素对糖尿病患病率的影响，并将与糖尿病有关的因素进行Logistic：回归分析。结果 单因素分析结果表明，年龄、糖尿病家族史、高血压、高血脂、冠心病、视网膜病变、体力活动、巨大儿生育史、收缩压、舒张压、脉搏、腰围、腰臀围比值、体质指数等21个指标与糖尿病相关；人均饮食费用、烟酒史、HBsAg及化工有害物质接触史与糖尿病无明显关联。经Logistic回归分析表明，与糖尿病关系最为密切的因素依次为：腰臀围比值、视膜膜病变、家族史、高血脂、年龄、腰围、脉搏、收缩压、职业及体力活动，其OR值分别为49．369、3．355、2．351、1．821、1．660、1．038、1．020、1．018、O．866及0．709。结论 阳性家族史、高年龄、高血脂、高收缩压、高脉率及腹型肥胖是糖尿病的主要危险因素；强体力活动及从事体力活动多的职业对糖尿病有保护作用；视网膜病变与糖尿病高度相关；人均饮食费用、烟酒史、HBsAg及化工有害物质接触史与糖尿病之间无明显关系。

A Study on Risk Factors for Diabetes in Personnel of Chemical Industry

Objective To investigation the main risk factors for diabetes in personnel of chemical industry.Method 6 387 adults aged 20 years and over in Sichuan Luzhou Chemical Group Corporation were surveyed with questionnaire,physical examination and blood analysis.DM was diagnosed according to the WHO Criteria of 1999.Prevalence was calculated and compared between groups and a Logistic model was fitted. Results 21 indexes were related to diabetes,they were age,family history of DM,blood pressure,hyperlipidemia,coronary heart disease,retinal disease,physical actives,history of macrosomia,systolic pressure,diastolic pressure,pulse,waistline,ratio of circumference of the waist to hip(WHR) and body mass index (BMI) etc.Average food charge,smoking and alcohol drinking,HBsAg and harmful chemical contamination history had no significant effects on diabetes.The Logistic regression analysis revealed that odds ratio (OR) of WHR,retinal disease,family history of DM,hyperlipidemia,age,waistline,pulse,systolic pressure,profession and physical activities were 49.369,3.355,2.351,1.821,1.660,1.038,1.020,1.018,0.866 and 0.709 respectively.Conclusions Family history of DM,age,hyperlipidemia,high systolic pressure,pulse and abdominal obesity are main risk factors for diabetes.Physical activities and manual-working profession can reduce the prevalence of diabetes.Retinal disease is closely related to diabetes.Average food charge,alcohol drinking,smoking,HBsAg and harmful chemical contamination history are not significantly related to diabetes.