头孢哌酮/舒巴坦联合左氧氟沙星治疗嗜麦芽寡养单胞菌肺炎的临床观察

目的 探讨头孢哌酮/舒巴坦联合左氧氟沙星治疗嗜麦芽寡养单胞菌肺炎的临床疗效.方法 对2009年3月-2011年10月使用头孢哌酮/舒巴坦联合左氧氟沙星治疗嗜麦芽寡养单胞菌肺炎的29例患者进行回顾性总结分析,对其临床疗效、细菌清除率、不良反应发生率进行观察.结果 29例患者经治疗后,临床总有效率68.97％,细菌清除率65.52％,不良反应发生率及死亡率均为10.34％.结论 头孢哌酮/舒巴坦联合左氧氟沙星治疗嗜麦芽寡养单胞菌肺炎效果好、细菌清除率高、安全性高,可作为嗜麦芽寡养单胞菌肺炎的经验性治疗.

Clinical observation on cefoperazone/sulbactam combined with levofloxacin in treating Stenotrophomonas maltophiliapneumonia

OBJECTIVE To observe the efficacy of cefoperazone/sulbactam combined with levofloxacin in treatment of Stenotrophomonas maltophilia pneumonia.METHODS The data were retrospectively collected from patients with S.maltophilia pneumonia treated by cefoperazone/sulbactam combined with levofloxacin from Mar 2009 to Oct 2011.The drug clinical efficacy,bacterial clearance rate and adverse reactions were reviewed.RESULTS The total response rate was 68.97% after 29 cases were treated with cefoperazone/sulbactam combined with levofloxacin.The bacterial clearance rate was 65.52%.The adverse reactions rate was 10.34%,and 3 cases died.CONCLUSION This study suggests that cefoperazone/sulbactam combined with levofloxacin may be an effective and safe treatment and has high bacterial clearance rate.Cefoperazone/sulbactam combined with levofloxacin is an important option for the empirical treatment of S.maltophilia pneumonia.