医院获得性肺炎危险因素及用药分析

目的 探讨医院获得性感染的危险因素及用药分析,从而指导临床治疗.方法 收集2010年12月-2011年12月住院的43200例患者临床资料,对医院获得性肺炎的危险因素及用药情况进行分析.结果 发生医院获得性感染患者736例,感染率为1.70％；患者年龄≥60岁、住院天数≥21 d、入住重症监护病房、存在基础疾病、抗菌药物的应用＞2种均为医院获得性肺炎的危险因素；青霉素类、抗感染类中成药、头孢菌素类、大环内酯类、氨基糖苷类的使用率分别为27.26％、25.07％、19.96％、16.04％、11.67％,中成药在治疗医院获得性肺炎中占有重要地位.结论 医院获得性肺炎的发生率较低,应根据该病的危险因素给予有针对性治疗,不可盲目联合给药.

Risk factors for hospital-acquired pneumonia and analysis of medication

OBJECTIVE To explore the risk factors for hospital-acquired pneumonia and analyze the medication so as to guide the clinical treatment.METHODS From Dec 2007 to Dec 2011,the clinical data of 43 200 patients were collected.The risk factors for hospital-acquired pneumonia and the drug application were analyzed.RESULTS The hospital-acquired pneumonia occurred in totally 736 patients with the infection rate of 1.70%.The patients aged more than 60 years,hospital stay more than 21 days,check in intensive care unit,the underlying diseases,and use of more than 2 antibiotics were the risk factors for the hospital-acquired pneumonia.The utilization rates of penicillin,traditional Chinese medicine for anti-infections,cephalosporins,macrolides,and aminoglycoside were 27.26%,25.07%,19.96%,16.04%,and 11.67%.respectively.Traditional Chinese medicine played an important role in the treatment of hospital-acquired pneumonia.CONCLUSION The incidence of hospital-acquired pneumonia is low in our hospital.The clinician should give targeted therapeutics and should not deliver combination therapies blindly.