蒙特利尔认知评估量表用于轻度认知功能障碍患者评估的初步研究

目的探讨中文版蒙特利尔认知评估量表(Montreal cognitive assessment scale,MoCA)用于轻度认知功能障碍(mild cognitive impairment,MCI)评估的可行性。方法选择MCI患者128例(MCI组),另选同期健康体检者101例(对照组)。分别给予MoCA和简易智能状态检查量表(MMSE)评估,并分析评估结果。结果对照组和MCI组MoCA总分与MMSE总分呈正相关(r=0.352,P<0.05;r=0.765,P<0.01);MoCA评分明显低于MMSE评分(P<0.01)。与对照组比较,MCI组MoCA总分及各亚项得分明显降低(P<0.01)。MoCA筛查MCI敏感性为97.66%,特异性为95.05%,MMSE筛查MCI敏感性为32.03%,特异性为100%。结论 MCI患者及健康体检人群MoCA总分与MMSE总分相关;MoCA用于MCI筛查时敏感性优于MMSE。

Application of Montreal cognitive assessment scale in assessment of mild cognitive impairment

Objective To study the application of Chinese version Montreal cognitive assessment (MoCA) scale in assessment of mild cognitive impairment(MCI).Methods One hundred and twenty-eight MCI patients served as a MCI group and 101 healthy subjects served as a control group in this study.Their cognitive function was assessed according to the MoCA and MMSE scales.Results The total score on the MoCA scale was positively correlated with that on the MoCA scale in MCI group and control group(r=0.352,P<0.05;r=0.765,P<0.01).The score was significantly lower on the MoCA scale than on the MMSE scale(P<0.01).The total score and other subitem scores on the MoCA scale were significantly lower in MCI group than in control group(P<0.05).The sensitivity and specificity of MoCA and MMSE scales were 97.66% and 95.05%,32.03%and 100%,respectively,for the detection of MCI.Conclusion The total score on the MoCA scale is related with that on the MMSE scale in MCI patients and healthy subjects. The sensitivity of MoCA scale is higher than that of MMSE scale in assessment of MCI.