Asthma: beyond corticosteroid treatment |
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| Authors: | Yasser Marandi Neda Farahi Goudarz Sadeghi Hashjin |
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| Affiliation: | 1.Department of Pharmacology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran;2.Division of Respiratory Medicine, School of Clinical Medicine, University of Cambridge, Cambridge, UK;3.Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran |
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| Abstract: | Asthma is one of the most common chronic diseases in the world, affecting over 300 million people. It is an inflammatory disorder characterized by bronchoconstriction and airway hyperresponsiveness, followed by inflammatory manifestations in the respiratory system. The prevalence of asthma is rising and there is a clinical need to develop more effective treatments. While corticosteroids (glucocorticosteroids) remain the mainstay of asthma therapy, they have limitations because of their potentially severe side-effects and the presence of corticosteroid resistance in some patients. This review discusses current strategies in the treatment of asthma and considers new therapeutic regimens of asthma in the drug development pipeline. |
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| Keywords: | asthma corticosteroids inflammation |
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