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Comparative anti-fertility effects of gossypol enantiomers in male hamsters |
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| Authors: | M. C. LINDBERG,R. H. NAQVI,S. A. MATLIN,R. H. ZHOU,G. BIALY&dagger ,R. P. BLYE&dagger |
| Affiliation: | EG&G Mason Research Institute, Worcester. |
| Abstract: | The enantiomers of gossypol have been tested as male oral anti-fertility agents in hamsters. As determined by fertility tests the (-) isomer was fully active at half the effective dose of the racemate, whereas the (+) isomer exerted no anti-fertility effect. |
| Keywords: | Gossypol isomers male anti-fertility agent |