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心脏骤停复苏后内皮细胞损伤与凝血关系的研究
引用本文:周景霞,陈治国,程瑞年. 心脏骤停复苏后内皮细胞损伤与凝血关系的研究[J]. 内科急危重症杂志, 2009, 15(2): 87-89
作者姓名:周景霞  陈治国  程瑞年
作者单位:承德市中心医院,承德,067000
摘    要:目的:探讨心脏骤停和成功复苏后内皮细胞损伤与凝血状态的变化、相关性及与预后的关系。方法:35例心脏骤停成功复苏患者,按照预后分为生存组和死亡组;健康正常人30例为对照组。分别测定血乳酸(LA),血管性假性血友病因子(vWF)和D-二聚体(D-dimer)水平。结果:死亡组和生存组的LA,vWF和D-dimer均高于对照组(P〈0.01),死亡组LA,vWF与D-dimer高于生存组(P〈0.05),复苏组LA,vWF与D-dimer呈明显正相关(P〈0.01),D-dimer与预后呈非常明显的负相关(r=-0.2903,P〈0.01)。结论:心脏骤停复苏成功患者存在组织和血管内皮细胞损伤及凝血功能紊乱,且二者存在相关性,D-dimer可能是判断预后的一种标记物。

关 键 词:心脏骤停  复苏  内皮细胞损伤  凝血

Research on the Correlation Between Endothelial Cell Damage and Blood Coagulation After Successful Cardiac Resuscitation
ZHOU Jingzia,CHEN Zhiguo,CHENG Ruinian. Research on the Correlation Between Endothelial Cell Damage and Blood Coagulation After Successful Cardiac Resuscitation[J]. Journal of Internal Intensive Medicine, 2009, 15(2): 87-89
Authors:ZHOU Jingzia  CHEN Zhiguo  CHENG Ruinian
Affiliation:ZHOU Jingxia,CHEN Zhiguo,CHENG Ruinian.The Center Hospital of Chengde,Chengde 067000,China
Abstract:Objective:To investigate the correlation between the endothelial cell damage and blood coagulation after successful cardiac resuscitation and it's prognosis.Methods:Thirty-five patients with successful cardiac resuscitation were divided into survival group and death group,30 healthy people as control group.Levels of lactic Acid(LA),vWF and D-dimmer were measured.Results:Levels of LA,vWF and D-dimer were higher in death group and survival group than those in control group(P<0.01),and Levels of LA,cWF and D-d...
Keywords:Sudden cardiac arrest Resuscitation Endothelial cell damage Coagulation  
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