| LONG TERM SUPPLEMENTATION OF SE-ENRICHED MALT FOR THE HIGH RISK POPULATION OF LUNG CANCER: INHIBITION OF ULTRAVIOLET LIGHT AND BENZOaPYRENE INDUCED UNSCHEDULED AND SYNTHESIS OF PERIPHERAL LYMPHOCYTES |
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| 引用本文： | 陈望秋,毛宝霖,肖平,于维平,王应龙,黄常志,褶湘珍. LONG TERM SUPPLEMENTATION OF SE-ENRICHED MALT FOR THE HIGH RISK POPULATION OF LUNG CANCER: INHIBITION OF ULTRAVIOLET LIGHT AND BENZOaPYRENE INDUCED UNSCHEDULED AND SYNTHESIS OF PERIPHERAL LYMPHOCYTES[J]. 中国癌症研究, 1993, 0(2) |
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| 作者姓名： | 陈望秋 毛宝霖 肖平 于维平 王应龙 黄常志 褶湘珍 |
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| 作者单位： | Cancer Institute，Chinese Academy of Medical Sciences，Beijing 100021，Labor Protection Institute of Yunnan Tin Corporation，Gejiu，Beijing Food Industrial Institute，Beijing.，Cancer Institute，Chinese Academy of Medical Sciences，Beijing 100021，Labor Protection Institute of Yunnan Tin Corporation，Gejiu，Cancer Institute，Chinese Academy of Medical Sciences，Beijing 100021，Labor Protection Institute of Yunnan Tin Corporation，Gejiu |
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| 摘 要： | Se malt cakes containing 300μg selenium were taken up daily to men from high risk area in lung cancer and the influences of Ultraviolet (UV) and Benaopyrene (BαP) induced unscheduled DNA synthesis (UDS) were determined. The Se levels in serum, hair and activity of GSH-px were increased by 89%, 67% and 178%, respectively, after Se-supplementation for half year. In the UV treatment, the ratio of UDS was decreased from the mean values of 2. 47 in the control to 1. 61 (P<0. 05) in the Se-group, In the BaP treatment, furthermore, the elevated Se levels of 78% in serum and 83% in the hair accompanied with 56% high in activity of GSH-px were followed by the Se intake for one year, while the mean value of UDS was reduced from 2. 21 in the control to 1. 47(P< 0. 05) in the group of selenium tested. The blocking effects of UV irradiation and BaP treatment induced UDS of peripheral lymphocytes were showed in the Se-supplementation.
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LONG TERM SUPPLEMENTATION OF SE-ENRICHED MALT FOR THE HIGH RISK POPULATION OF LUNG CANCER: INHIBITION OF ULTRAVIOLET LIGHT AND BENZOaPYRENE INDUCED UNSCHEDULED AND SYNTHESIS OF PERIPHERAL LYMPHOCYTES |
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| Chen Wangqiu Mao Baolin Xiao Ping Yu Weiping Wang Yinglong Huang Changzhi Xuan XiangzhenCancer Institute,Chinese Academy of Medical Sciences,Beijing ,Labor Protection Institute of Yunnan Tin Corporation,Gejiu,Beijing Food Industrial Institute,Beijing.. LONG TERM SUPPLEMENTATION OF SE-ENRICHED MALT FOR THE HIGH RISK POPULATION OF LUNG CANCER: INHIBITION OF ULTRAVIOLET LIGHT AND BENZOaPYRENE INDUCED UNSCHEDULED AND SYNTHESIS OF PERIPHERAL LYMPHOCYTES[J]. Chinese Journal of Cancer Research, 1993, 0(2) |
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| Authors: | Chen Wangqiu Mao Baolin Xiao Ping Yu Weiping Wang Yinglong Huang Changzhi Xuan XiangzhenCancer Institute Chinese Academy of Medical Sciences Beijing Labor Protection Institute of Yunnan Tin Corporation Gejiu Beijing Food Industrial Institute Beijing. |
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| Affiliation: | Chen Wangqiu Mao Baolin Xiao Ping Yu Weiping Wang Yinglong Huang Changzhi Xuan XiangzhenCancer Institute,Chinese Academy of Medical Sciences,Beijing 100021,Labor Protection Institute of Yunnan Tin Corporation,Gejiu,Beijing Food Industrial Institute,Beijing. |
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| Abstract: | |
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| Keywords: | Unscheduled DNA synthesis (UDS).Selenium Ultraviolet Benzopyrene |
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