舒血宁注射液治疗急性脑梗死80例的疗效观察

目的:观察舒血宁注射液治疗急性脑梗死的临床疗效。方法:将80例急性脑梗死患者按住院单双号随机分为治疗组和对照组。治疗组给予舒血宁注射液15~20ml溶于生理盐水或5%葡萄糖250ml静脉点滴,每天1次。对照组给予复方丹参注射液250ml静脉点滴,每天1次。两组同时使用自由基清除剂、钙离子拮抗剂、脑细胞保护剂治疗。伴有高血压病者给予调控血压治疗,伴有脑水肿者给予脱水治疗。两组疗程均为14d。于治疗前后各进行一次临床神经功能缺损程度评分及血液流变学检测。治疗过程中检测TT、PT、APTT、纤维蛋白原和血小板计数,血、尿常规,肝、肾功能。结果:治疗组痊愈率、总有效率明显高于对照组(P<0.05)。治疗组神经功能缺损评分及血液流变学指标较治疗前显著降低(P<0.05),而且较对照组明显。结论:舒血宁注射液可促进神经功能恢复,显著降低血液黏稠度,临床疗效显著。

Clinical Observation of Shuxuening Injection Treated on 80 Cases with Acute Cerebral Infarction

Objective：To study on the clinical effect of Shuxuening injection on acute cerebral infarction. Methods： 80 patients with acute cerebral infarction were divided into treatment group and control group randomly by odd and even hospitalization numbers. The patients in treatment group were treated with intravenous drip of Shuxuening injection, a dose of 15-20ml which was dissolved in 250ml normal saline or 5% dextrose, quaque die. The patients in control group were treated with intravenous drip of 250ml composite salvia injection, quaque die All cases were treated with free radicat scavenger, calcium antagonist and brain cell protective agent. The patients accompanied by hypertension were given the treatment of controlling blood pressure,and the patients accompanied by brain edema were given the dehydration treatment. The courses of treatment of two groups were both 14 days. The neurological deficit scores and hemorheology detection were made pre and post treatment. The indexes in the course of the treatment were detected, which were TT, PT, APTT, fibrinogen, platelet count, and blood routine urine routine, hepatic and renal function. Results： The cure rate and total effective rate in treatment group were obviously better than those of the control group （P〈0.05）. The decreased degree in treatment group, which is that the data of neurological deficit scores and hemorheology indices was significantly lower after treatment, was better than that in control group （P〈 0. 05）. Conclusion： Shuxuening injection could promote nerve recovery and decrease blood viscosity, clinical effect of which is significant.