加味藿香正气散联合西药治疗腹泻型肠易激综合征临床研究

目的：观察加味藿香正气散联合匹维溴胺与黛立新治疗腹泻型肠易激综合征（IBS—D）的疗效。方法：将102例患者随机分为2组，对照组用匹维溴胺和黛立新治疗，治疗组用加味藿香正气散联合匹维溴胺与黛立新治疗，疗程4周，在治疗结束时记录患者症状改善等情况，根据症状评分综合分析2组的疗效。结果：2组患者在治疗后症状均有改善（P〈0．01）；但治疗组症状改善比对照组更明显（P〈0．01）；总有效率治疗组92．0％，对照组78．8％，2组比较，差异有非常显著性意义（P〈0．01）。结论：加味藿香正气散联合匹维溴胺与黛立新治疗IBS～D有良好疗效，且无毒副反应。

Clinical Study of Jiawei Huoxiang Zhengqi Powder Combined with Western Medicine for Treatment of Diarrhea-predominant Irritable Bowel Syndrome

Objective： To observe the therapeutic effects of Jiawei Huoxiang Zhengqi Powder combined with pinaverium bromide and flupentixol-melitracen for diarrhea-predominant irritable bowel syndrome（IBS-D）. Methods： One hundred and two patients were randomly divided into control group and treatment group. The two groups were treated with pinaverium bromide and flupentixol-melitracen, and the treatment group received Jiawei Huoxiang Zhengqi Powder additionally. The treatment course lasted four weeks. After treatment, the relief of symptoms was observed, and the therapeutic effect of two groups was evaluated according to the scores of symptoms. Results： The symptoms were much relieved in both groups after treatment（P 〈 0.01 compared with those before treatment）, the relief in the treatment group being superior to that in the control group（P 〈 0.01）. The total effective rate was 92.0% in the treatment group and 78.8% in the control group, the difference being significant （P 〈 0.01）. Conclusion： Jiawei Huoxiang Zhengqi Powder combined with pinaverium bromide and flupentixol-melitracen is effective and safe for treatment of IBS-D.