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红细胞撞击损伤机理研究及仿真分析
引用本文:云忠,谭建平,徐先懂. 红细胞撞击损伤机理研究及仿真分析[J]. 生物医学工程研究, 2006, 25(1): 20-23,27
作者姓名:云忠  谭建平  徐先懂
作者单位:中南大学机电工程学院,湖南,长沙,410083;中南大学机电工程学院,湖南,长沙,410083;中南大学机电工程学院,湖南,长沙,410083
基金项目:国家自然科学基金资助项目(50275151)
摘    要:采用薄壁球壳理论及液滴激波理论,研究了旋转叶轮血泵中红细胞-叶片撞击损伤机理,给出了红细胞撞击压力表达式及红细胞膜极限应力数值,并采用ALE有限元法对撞击过程进行仿真,分析不同撞击速度下红细胞形状及应力变化,得到了临界撞击速度数值,并进行了实验验证。

关 键 词:红细胞  撞击  损伤  溶血  仿真
文章编号:1672-6278(2006)01-0020-04
收稿时间:2006-01-15
修稿时间:2006-01-15

Study and Simulation Analysis on the Hurt Principle of the RBC Impact
YUN Zhong,TAN Jian-ping,XU Xian-dong. Study and Simulation Analysis on the Hurt Principle of the RBC Impact[J]. Journal Of Blomedical Englneerlng Research, 2006, 25(1): 20-23,27
Authors:YUN Zhong  TAN Jian-ping  XU Xian-dong
Abstract:The hurt principle of the impact between RBC and impeller in the rotated impelled blood pump is studied by using the theory of thinner sphere shell and the theory of liquid drop.The impact stress equation and the extreme stress value of the impacted RBC are presented.The process simulation of the impact is carried out by using ALE finite element method.The RBC variation of the shape and stress at different impact speed are analyzed.The critical impact speed is obtained,and the result is proved by experiment.
Keywords:Red blood cell  Impact  Hurt  Hemolysis  Simulation
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