Characterization of a new HLA‐A allele,HLA‐A*02:07:08, by cloning and sequencing |
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| Authors: | W Y Wang W Zhang L X Li F M Zhu W Tian |
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| Institution: | 1. Immunogenetics Research Group, Department of Immunology, College of Basic Medical Sciences, Central South University, Changsha, China;2. HLA Typing Laboratory, Blood Center of Zhejiang Province, Hangzhou, Zhejiang, China;3. Key Laboratory of Blood Safety Research, Ministry of Health, Hangzhou, China;4. Laboratory of Cellular and Molecular Biology, College of Basic Medical Sciences, Central South University, Changsha, China |
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| Abstract: | In this report, we present a novel HLA‐A*02:07 allele, HLA‐A*02:07:08. HLA‐A*02:07:08 was identified in an individual of Han ethnicity in Hunan province, southern China. Following polymerase chain reaction‐sequence‐based typing (PCR‐SBT), this new allele was further confirmed by cloning and sequencing. HLA‐A*02:07:08 differs from HLA‐A*02:07:01 by a single synonymous C to T substitution at nucleotide position 131 in exon 3. |
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