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习惯性流产与几种自身抗体的关系
引用本文:吴锦芝,洪莉娟.习惯性流产与几种自身抗体的关系[J].标记免疫分析与临床,1996,3(3):123-125,133.
作者姓名:吴锦芝  洪莉娟
作者单位:中国福利会国际和平妇幼保健院
摘    要:本文对316例不明原因的习惯性流产者,用酶联免疫分析进行抗心磷脂抗体(ACA)、抗血小板抗体(PA)及抗脱氧核糖核酸抗体(抗DNA)测定,并与正常人比较。结果流产组ACA、PA、抗DNA阳性率分别为23.7%、16.7%、13.6%,均显著高于正常对照组(P分别为〈0.01,〈0.01,〈0.05),其中以ACA-IgG、ACA-IgM、PA-IgG、PA-IgM及ss-DNA为主,它们与习惯性流

关 键 词:流产  习惯性  自身抗体

Relationship Between Recurrent Spontaneous Abortion and Certain Autoantibodies
Shen Yuchen, Wu Jinzhi, Hong Lijuan.Relationship Between Recurrent Spontaneous Abortion and Certain Autoantibodies[J].Labeled Immunoassays and Clinical Medicine,1996,3(3):123-125,133.
Authors:Shen Yuchen  Wu Jinzhi  Hong Lijuan
Abstract:Anticardiolipin antibody (ACA),Platelet associated immunoglobulin (PA) and Antibodies against DNA were measured with enzyme linked immunosorbent assay (ELISA) in healthy volunteers (normal control) and 316 cases of recurrent spontaneous abortion of unknown origin (abortion group). The positivity for ACA, PA and anti-DNA in the abortion group was 23. 7%, 16. 7% and 13. 6%, respectively, being significantly higher than those in the normal control ( P < 0. 01,P < 0.01,P <0. 05). The relationship between ACA-IgG.ACA-IgM,PA-IgG,PA-IgM,anti-ssDNA and recurrent spontaneous abortion is obvious.The study shows that ACA-IgG,ACA-IgM,PA-IgG,PA-IgM and anti-ss DNA tests will be helpful to disclose the etiology of recurrent spontaneous abortion of unknown origin.
Keywords:Abortion  habitual Autoantibodies Antibodies  anticardiolipins Platelet associated immunoglobulin Antibodies  anti-DNA  
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