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表皮细胞生长因子对烧伤后膝关节创面愈合和功能的影响
引用本文:张显文,柳晖,陈武鹏.表皮细胞生长因子对烧伤后膝关节创面愈合和功能的影响[J].中国组织工程研究与临床康复,2001,25(18):39.
作者姓名:张显文  柳晖  陈武鹏
作者单位:深圳市宝安人民医院
摘    要:目的探讨人表皮细胞生长因子(rhEGF)对烧伤后膝关节的创面愈合和功能影响.方法44例膝关节部位深Ⅱ度烧伤患者分为治疗组(22例,27只)用rhEGF100IU/m2局部喷洒创面;对照组(22例,27只)用溶媒喷洒创面.结果治疗组平均创面愈合时间短,膝关节外观异常发生率和关节活动度(ROM)关节功能评分均明显优于对照组(P均<0.05).结论rhEGF有助于烧伤后膝关节的创面愈合和功能恢复.

关 键 词:表皮细胞生长因子    膝关节    烧伤    创面愈合    功能
文章编号:1007-5496(2001)09-0039-01
修稿时间:2001年7月15日

Effect of recombinant human epidermal growth factor(rhEGF) on wound healing and knee joint function after burn
ZHANG Xi-an -wen,LIU Hui,CHEN Wu -peng,Baoan People' s Hospital of Shenzhen city,Shenzhen ,China.Effect of recombinant human epidermal growth factor(rhEGF) on wound healing and knee joint function after burn[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2001,25(18):39.
Authors:ZHANG Xi-an -wen  LIU Hui  CHEN Wu -peng  Baoan People' s Hospital of Shenzhen city  Shenzhen  China
Institution:ZHANG Xi-an -wen,LIU Hui,CHEN Wu -peng,Baoan People' s Hospital of Shenzhen city,Shenzhen 518101,China
Abstract:Objective To explore the effect of rhEGF on knee joint function and wound healing after burn.Method44cases patients with deep second -degree burn were ra ndomly divided into treatment group and control group.The wounds of trea tment group were applied with doses of rhEGF(100IU /cm2)once a day with moistening.Control g roup with normal saline was employed as control agents.The wound healing time,external form and knee joint function were compared with ea ch other.Result The wound healing time in treatment g roup is significantly shorted than that in t he control group.The abnormal rate o f knee joint,external form,ROM,and joint function scale in treatment group were superior to control group.Conclusion rhEGF is helpful to the wound healing and function recover of burned knee j oint.
Keywords:recombinant human epidermal growth factor(rhEGF)  knee joint  wound of burning  wound healing  function
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