原发肠道恶性纤维组织细胞瘤——临床病理及超微结构观察

本文报告6例原发肠道恶性纤维组织细胞瘤,其中发生在小肠3例,回盲部、降结肠及乙状结肠各1例。镜下肿瘤主要由纤维母细胞样细胞和组织细胞样细胞构成,在二者之间有胖梭形过渡细胞。组织细胞样细胞可演变为泡沫细胞和多核、单核的瘤巨细胞,另见少量未分化间叶细胞。对其中2例进行了电镜超微结构的观察。

PRIMARY MALIGNANT FIBROUS HISTIOCYTOMA OF THE GUT

Six cases of primary malignant fibrous histiocytoma of the gut from 1974 thro- ugh 1985 were reported. 4 were males, 2 females, aged 28-64 years. Of the 6 cases, 4 occured in small intestine and 2 in colon. Histologically, MFH is pleomorphic, the histiocyte-like cells and fibroblast-like ceils were detected predominatly. The transitional cells between the two cell types were also seen. The histiocyte-like ce- lls may be transformed into foamy cells, mononucleated or multinucleated tumor giant cells. Undifferentiated mesenchymal cells were rarely seen. Two cases were studied with electron microscopy.