结核性脑膜炎脑脊液中LDH,AST,CK动态观察

目的 研究结核性脑膜炎（结脑）患者脑脊液（ＣＳＦ）中乳酸脱氢酶（ＬＨＤ）、谷草转氨酶（ＡＳＴ）、肌酸激酶（ＣＫ）的动态变化。方法 用日立全自动生化分析仪按酶测速率法对３８例结脑患者、３１例对照组ＣＳＦ中ＬＤＨ，ＡＳＴ，ＣＫ活性进行测定。结果结脑急性期３种酶活性均显著高于正常对照组及恢复期，恢复期ＣＳＦ中３种酶活性与对照组比较无显著性差异，ＣＳＦ中３种酶活性与ＣＳＦ中蛋白浓度及细胞数无相关。结论：Ｃ

DYNAMICAL RESEARCH OF LACTIC DEHYDROGENASE ASPARTATE AMINOTRANSFERASE AND CREATINE KINASE ACTIVITY IN CSF OF TUBERCULOUS MENINGITIS

Objective: To study the dynamical change in lactic dehydrogenase (LDH),aspartate aminotransferase (AST) and creatine kinase (CK) activity in CSF of tuberculous menigitis Methods: LDH,AST,CK activity of 38 tuberculous meningitis patients were measured by rate method using fresh specimen in HITACH analyzer31 cases without neurological disorder were used as control Result: LDH,AST,CK activity in acute period were markedly elevated than those in nomal control group and convalescenceLDH,AST,CK activity of convalescence were similar to those of control groupNeither concentration of protein nor number of cell have correlation with LDH,AST,CK activity in CSF Conclusion: The measurement of LDH,AST and CK activity can not only be used as an auxiliary diagnosis method of tuberculous meningitis,but can also tell us how serious the injury of cerebral tissueThe dynamical research of enzyme in CSF can give us some information of prognosis of tuberculous meningitis