肺原发性淋巴瘤的CT影像学特点及文献复习

目的：分析肺原发性淋巴瘤患者的影像学及临床表现特征,提高对于该疾病的诊断和鉴别诊断能力。方法：回顾性分析经病理明确诊断的肺原发淋巴瘤患者的CT影像学表现,结合相关文献,总结肺部原发淋巴瘤的影像学表现特点。结果：10例肺原发性淋巴瘤患者中,7例确诊为黏膜相关淋巴组织淋巴瘤（mucosa-associated lymphoid tissue, MALT）淋巴瘤,1例确诊为弥漫大B细胞淋巴瘤,2例确诊为外周T细胞淋巴瘤。8例患者的CT图像上病灶可见支气管充气征,9例增强CT均可见病灶轻度强化及血管漂浮征,8例可见晕征,而患者的临床表现均无特异性。结论：肺部原发性淋巴瘤患者的影像学表现复杂多样,且临床和影像学表现无特异性,空气支气管征、增强后病灶呈轻中度强化、血管漂浮征、晕征等为肺部淋巴瘤在CT图像上较为特征的征象。

Analysis of CT imaging characteristics of primary pulmonary lymphoma and review of literature

Objectives: To analyze the imaging features of primary pulmonary lymphoma and to differentiate it from other pulmonary tumors. Methods: CT imaging of patients proved by pathology as primary pulmonary lymphoma were analyzed retrospectively, and relevant literatures were reviewed. Results: Ten patients were enrolled in this study,7 patients were confirmed as mucosa-associated lymphoid tissue lymphoma (MALT),1 patient was diffuse large B cell lymphoma (DLBCL), and 2 patients were peripheral T-cell lymphoma. Air bronchogram could be seen in 8 patients. Vessel floating sign and mild enhancement could be seen in 9 patients.Halo sign could be seen in the edge of lesion in 8 patients. There were no special features in clinical manifestation. Conclusions: The imaging of primary lymphoma of lung is complicated and varied. There is no specific feature in both CT and clinical features. Air bronchogram, mild enhancement, vessel floating sign and halo sign could be the relatively specific sign of primary lymphoma in lung. The diagnosis of primary lymphoma in lung depends on pathological examination. For differential diagnosis, immunohistochemical staining and molecular pathological examination may be helpful.