2型糖尿病合并戊型肝炎患者的临床特征分析

目的：探讨2型糖尿病合并戊型肝炎患者的临床特征。方法：回顾性分析119例2型糖尿病合并戊型肝炎患者的性别、年龄等临床特征,另设无肝炎的2型糖尿病组（单纯糖尿病组）及单纯戊型肝炎组患者作为对照,比较3组的实验室检查结果。结果：2型糖尿病合并戊型肝炎组中,50~69岁年龄段的患病人数较多（占65%）。2型糖尿病合并戊型肝炎组患者的糖化血红蛋白（hemoglobinA1c, HbA1C）水平低于单纯糖尿病组患者（8.0±1.8）%比（8.4±2.0）%]（P<0.01）,但2组间比较空腹血糖及餐后血糖差异无统计学意义（P>0.05）;2型糖尿病合并戊型肝炎组的总胆红素及天冬氨酸转氨酶明显低于单纯戊型肝炎组（P<0.05）;单纯糖尿病组、单纯戊型肝炎组、2型糖尿病合并戊型肝炎组这3组间比较的肾功能、血脂指标差异均无统计学意义（P>0.05）。结论：2型糖尿病合并戊型肝炎患者的HbA1c低于单纯糖尿病患者,其余血糖指标没有差异;与单纯戊型肝炎组患者相比,2型糖尿病合并戊型肝炎组患者的肝功能并没有出现进一步的减退。

Clinical characteristics of type 2 diabetes complicated with hepatitis E

Objective: To study the clinical characteristics of type 2 diabetes mellitus complicated with hepatitis E.Methods: The clinical characteristics of 119 type 2 diabetes patients complicated with hepatitis E were retrospectively analyzed. The results were compared with type 2 diabetes patients without hepatitis E (simpletype 2 diabetes mellitus) and with simple hepatitis E patients. Results: The number of patients between 50-69 years of age was higher in type 2 diabetes complicated with hepatitis E group (65%). HbA1C was lower than that in simple type 2 diabetes group（P<0.01）. There were no statistical significant differences between the two groups in fasting and postprandial blood glucose（P>0.05）. Compared with simple hepatitis E group, total bilirubin and AST were lower in type 2 diabetes patients complicated with hepatitis E（P<0.05）. There were no significant differences in renal function and blood lipid indexes between these three groups. Conclusions: HbA1C in type 2 diabetes patients complicated with hepatitis E was lower than that in patients with type 2 diabetes alone.Thereare no significant differences in other blood glucose indice. Compared with simple hepatitis E patients, there was no further decline in liver function in type 2 diabetes patients complicated with hepatitis E. The three groups had no significant differences in renal function and blood lipid indice.