| 天然山泉水对老龄小鼠SOD和MDA含量的影响 |
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| 引用本文： | 康爱君.天然山泉水对老龄小鼠SOD和MDA含量的影响[J].中国比较医学杂志,2015,25(10):34-37. |
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| 作者姓名： | 康爱君 |
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| 作者单位： | 北京大学医学部实验动物科学部, 北京 100191;北京大学医学部实验动物科学部, 北京 100191;北京大学医学部实验动物科学部, 北京 100191;北京大学医学部实验动物科学部, 北京 100191;北京大学医学部实验动物科学部, 北京 100191;北京大学医学部实验动物科学部, 北京 100191 |
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| 摘 要： | 目的 探讨天然山泉水对老龄小鼠脂质过氧化水平的影响。方法 8月龄SPF级雄性ICR小鼠适应性饲养5 d后,禁食16 h,取血,测血清丙二醛(MDA)含量。根据MDA含量,将ICR小鼠随机分为两组:天然山泉水组和自来水对照组。天然山泉水组自由饮用天然山泉水,自来水对照组自由饮用自来水,连续饮用两个月,饮用1个月和两个月时禁食16 h,取血,测血清丙二醛(MDA)含量和超氧化物歧化酶(SOD)活力。结果 给予天然山泉水两个月后,与自来水对照组相比,天然山泉水组丙二醛(MDA)含量显著降低(P<0.05),超氧化物歧化酶(SOD)活力无显著性差异。结论 饮用天然山泉水对缓解老龄小鼠脂质过氧化水平有一定的作用。
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| 关 键 词： | 天然山泉水 老龄小鼠 超氧化物歧化酶 丙二醛 |
| 收稿时间： | 7/3/2015 12:00:00 AM |
| 修稿时间： | 8/5/2015 12:00:00 AM |
Effect of natural mountain spring on SOD and MDA content in mice aging |
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| kangaijun.Effect of natural mountain spring on SOD and MDA content in mice aging[J].Chinese Journal of Comparative Medicine,2015,25(10):34-37. |
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| Authors: | kangaijun |
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| Institution: | Department of Laboratory Animal Science, Health Science Center, P. K. U. Beijing 100191, China;Department of Laboratory Animal Science, Health Science Center, P. K. U. Beijing 100191, China;Department of Laboratory Animal Science, Health Science Center, P. K. U. Beijing 100191, China;Department of Laboratory Animal Science, Health Science Center, P. K. U. Beijing 100191, China;Department of Laboratory Animal Science, Health Science Center, P. K. U. Beijing 100191, China;Department of Laboratory Animal Science, Health Science Center, P. K. U. Beijing 100191, China |
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| Abstract: | Objective To observe the effect of Natural mountain spring on oxidative damage of aging mice. Methods Thirty male aging mice were randomly divided into experimental group(drink Natural mountain spring) and control group(drink tap water) according to the level of MDA. The serum in the two groups was taken for T-SOD activity and MDA content analysis after two months. Results The MDA content in experimental group decreased markedly than that in control group. Conclusion Natural mountain spring could alleviate oxidative damage by free radicals to extent. |
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| Keywords: | Natural mountain spring Aging mice Superoxide dismutase Malondialdehyde |
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