超敏C反-应蛋白与冠心病各类型病变的因果关系

目的了解超敏-C反应蛋白（hs-CRP）与冠心病（CHD）不同类型病变的发生、发展因果关系,以便研究采取防治措施。方法选择CHD患者90例,其中包括急性心肌梗死（AM I）35例,不稳定性心绞痛（UAP）25例,稳定性心绞痛SAP 30例。采用免疫浊度法,测其患者血清内的hs-CRP含量,并进行对比分析和讨论。结果 CHD总体和各类型（AM I、UAP、SAP）的hs-CRP浓度与健康人对照组（NC）的结果比较,各类型CHD hs-CRP含量均高于对照组,差异有统计学意义（P〈0.01）;各类型CHD病变的hs-CRP异常百分率分别为UAP（88%）〉AM I（85.7%）〉SAP（53.7%）。UAP、AM I与SAP比较,差异均有统计学意义（P〈0.01）。结论 hs-CRP与CHD多种危险因素有关,hs-CRP水平是反映冠状动脉粥样病变的炎症、炎性反应的主要指标,对预测CHD各类型病变动态及心血管事件有重要价值。

Causality between Hs-CRP and Different Types of Coronary Heart Disease

[Objective]To understand the causality between high-sensitivity C-reactive protein(hs-CRP) and occurrence and development of different types of coronary heart disease(CHD),in order to study and adopt control measures.[Methods]90 CHD patients were selected,which included 35 cases of acute myocardial infarction(AMI),25 cases of unstable angina pectoris(UAP) and 30 cases of stable angina pectoris(SAP).The serum hs-CRP levels were tested by immune turbidimetry method,and were analyzed and discussed.[Results]The...