| 生酮饮食对兔心肌缺血再灌注损伤的保护 |
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| 引用本文： | 刘志强,崔利德. 生酮饮食对兔心肌缺血再灌注损伤的保护[J]. 职业与健康, 2011, 27(15): 1736-1737 |
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| 作者姓名： | 刘志强 崔利德 |
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| 作者单位： | 济宁医学院人体解剖教研室,山东省日照市,276826 |
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| 摘 要： | 目的探讨生酮饮食(KD)对兔心肌缺血再灌注损伤影响。方法分别给予雄性兔正常饮食(normal diet,ND)和KD6周后,结扎免冠状动脉左前降支30 min后,恢复再灌注180 min,通过观察心电图、心肌酶学和心肌梗死范围指标,评价KD对兔心肌缺血再灌注损伤的保护作用。结果 A组(ND+假手术组)乳酸脱氢酸、肌酸激酶活力未升高,心电图无变化,心肌无梗死。B组(ND+缺血再灌注组)变化明显。C组(KD+缺血再灌注组)较B组轻。结论用KD干预后,兔心肌缺血再灌注损伤减轻。
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| 关 键 词： | 生酮饮食 缺血再灌注损伤 兔 |
Protective Function of KD on Myocardial Ischemia-reperfusion Injury in Rabbit |
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| LIU Zhi-qiang,CUI Li-de. Protective Function of KD on Myocardial Ischemia-reperfusion Injury in Rabbit[J]. Occupation and Health, 2011, 27(15): 1736-1737 |
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| Authors: | LIU Zhi-qiang CUI Li-de |
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| Affiliation: | LIU Zhi-qiang,Cui Li-de(Jining Medical College,Rizhao,276826,China) |
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| Abstract: | [Objective]To discuss the effect of Ketogenic diet(KD) on myocardial ischemia-reperfusion injury in rabbit.[Methods]After pretreatment normal diet(ND) and KD respectively in male rabbits for 6 weeks,all the rabbits were ligated with the left anterior descending coronary arteries for 30 min and then recovered reperfusion for 180 min.The protection of KD on myocardial ischemia-reperfusion injury was evaluated by monitoring of ECG and serum creatine kinases,and myocardial infarct size measurements.[Results]In ... |
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| Keywords: | Ketogenic diet(KD) Ischemia-reperfusion injury Rabbit |
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