| 牙周引导组织再生壳聚糖膜的生物相容性研究 |
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| 引用本文： | 张毅,庄昭霞,卢凤琦,曹宗顺.牙周引导组织再生壳聚糖膜的生物相容性研究[J].山东大学学报(医学版),2002,40(2):115-117. |
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| 作者姓名： | 张毅 庄昭霞 卢凤琦 曹宗顺 |
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| 作者单位： | 1. 山东大学,口腔医院
2. 山东大学,药学院 |
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| 基金项目： | 山东省自然科学基金资助课题 (Y98CO90 38) |
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| 摘 要： | 目的 :观察壳聚糖作为牙周引导组织再生膜的生物相容性。方法 :采用冷冻干燥法制备壳聚糖膜 ,然后通过细胞毒性试验、溶血试验、热原试验、过敏试验等体内外生物学试验相结合的方法研究其生物相容性。结果 :测试表明壳聚糖膜无毒、不溶血、不致热、不致敏。结论 :壳聚糖膜具有良好的生物相容性。
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| 关 键 词： | 壳聚糖 生物相容性 引导组织再生 |
| 文章编号： | 1671-7554(2002)02-0115-03 |
| 修稿时间： | 2001年8月28日 |
Biocompatibility of chitosan as membrane for periodontal guided tissue regeneration |
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| ZHANG Yi,ZHUANG Zhao xia,LU Feng qi,et al.Biocompatibility of chitosan as membrane for periodontal guided tissue regeneration[J].Journal of Shandong University:Health Sciences,2002,40(2):115-117. |
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| Authors: | ZHANG Yi ZHUANG Zhao xia LU Feng qi |
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| Abstract: | Objective: To investigate the biocompatibility of chitosan as membrane for periodontal guided tissue regeneration (GTR). Methods: Chitosan membrane was prepared by freeze drying and tests in vitro and in vivo including cytotoxicity test, haemolysis test, hypersesitive test and pyrogen test, were employed to investigate its biocompatibility. Results: Chitosan membrane showed no toxicity and did not cause hemolysis, pyrogen or hyperergia. Conclusion: Chitosan has desirable biocompatibility. |
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| Keywords: | Chitosan Biocompatibility guided tissue regeneration |
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