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Unresolved pulmonary embolism leading to a diagnosis of pulmonary artery sarcoma
Affiliation:1. Cleveland Clinic, Research Department of Molecular Cardiology, Cleveland, OH 44195, USA;2. Department of Internal Medicine, Section of Pulmonary, Critical Care, & Sleep Medicine, Yale University, School of Medicine, New Haven, CT 06510, USA;3. Department of Pathology and Cell Biology, Columbia University Medical Center, USA;4. Department of Surgery, Section of Thoracic Surgery, Columbia University Medical Center, USA;1. University of Pittsburgh, Pittsburgh, PA, USA;2. The State University of New York University at Buffalo, Buffalo, NY, USA;3. The VA of WNY Healthcare System, Buffalo, NY, USA;4. The Strong Memorial Hospital at University of Rochester Medical Center, Rochester, NY, USA;1. Indiana Wesleyan University, Marion, IN, USA;2. VA Loma Linda Healthcare System, Loma Linda, CA, USA;1. Nursing Department, School of Health Sciences, Cyprus University of Technology, 15 Vragadinou Str., 3041 Limassol, Cyprus;2. Department of Health Science, School of Sciences, European University Cyprus, 6, Diogenes Str., Engomi, P.O. Box 22006, 1516 Nicosia, Cyprus;3. Faculty of Nursing, University of Athens, 123 Papadiamantopoulou Str., Goudi, Athens 11527, Greece;4. Cardiology Department, American Medical Center/American Heart Institute, Cyprus;5. Cardiology Department, Larnaca General Hospital, 1 Pandoras, Larnaca, Cyprus;1. Department of Acute and Tertiary Care, School of Nursing, University of Pittsburgh, PA, USA;2. VA WNY Health Care System at Buffalo, USA;3. Department of Medicine at The University at Buffalo, NY, USA;4. Department of Physiology & Biophysics at The University at Buffalo, NY, USA;5. Department of Biomedical Engineering at The University at Buffalo, NY, USA;6. Center for Research in Cardiovascular Medicine at The University at Buffalo, NY, USA;7. Strong Memorial Hospital at University of Rochester Medical Center, Rochester, NY, USA
Abstract:Pulmonary artery sarcomas (PAS) are rare tumors with a poor prognosis. They are often misdiagnosed as pulmonary embolism (PE) leading to futile anticoagulation treatment and delay in proper diagnosis. We present a case of a patient who was initially misdiagnosed and anticoagulated for presumed pulmonary embolism. Progressive symptoms and additional imaging led to the diagnosis of intimal pulmonary artery sarcoma for which he underwent surgical resection. This case serves as a reminder to consider pulmonary artery sarcoma in the differential diagnosis of patients with dyspnea and filling defects on CT pulmonary angiogram offering the potential for resection prior to metastasis.
Keywords:Neoplasm  Radiography  Pulmonary embolism  Diagnosis  Differential  Sarcoma  Pulmonary hypertension
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