Prophylactic use of heparin for deep vein thrombosis in restrained psychiatric patients: a chart review |
| |
| Affiliation: | 1. Department of Psychiatry, Sakuragaoka Memorial Hospital, Tokyo, Japan;2. Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan;3. Department of Psychiatry, Inokashira Hospital, Tokyo, Japan;4. Department of Neuropsychiatry, Kyorin University School of Medicine, Tokyo, Japan;5. Geriatric Mental Health Program, Centre for Addiction and Mental Health, Toronto, ON, Canada;1. Institute of General Practice, Goethe-University Frankfurt am Main, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany;2. Institute of Medical Biostatistics, Epidemiology and Informatics, University Mainz, Obere Zahlbacher Str. 69, 55131 Mainz, Germany;3. Institute of General Practice and Family Medicine, Jena University Hospital, Friedrich Schiller University, Bachstraße 18, 07743 Jena, Germany;1. National Centre for Suicide Research and Prevention, Institute of Clinical Medicine, University of Oslo, Norway;2. Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA;3. Molecular Imaging and Neuropathology Division and Suicide Prevention Training, Implementation and Evaluation Program in the Center for Practice Innovation, New York State Psychiatric Institute, New York, NY, USA;4. Department of Biostatistics, Epidemiology and Health Economics, Oslo University Hospital, Norway;1. Department of Neurosciences: Sciences NPSRR, University of Padova, Padova, Italy;2. IRCCS San Camillo Hospital Foundation, Venice, Italy;3. Department of Medicine (DIMED), University of Padova, Padova, Italy |
| |
| Abstract: | ObjectivePhysical restraint sometimes causes deep vein thrombosis (DVT) and pulmonary embolism. Although unfractionated heparin (UFH) is used for the prophylaxis of DVT, its effectiveness remained unknown for restrained patients.MethodWe conducted a chart review of restrained inpatients at Sakuragaoka Memorial Hospital in Japan. Restrained patients received subcutaneous injection of UFH 5000 IU bid from December 2008 to September 2010 [heparin (+) period] while UFH was not used from December 2010 to September 2012 [heparin (−) period]. A Doppler ultrasound scanning was performed to examine the presence of DVT. The incidence of DVT was compared between the two periods by chi-square test. A multiple logistic regression model was used to examine effects of demographic and clinical characteristics on the incidence of DVT.ResultsNo significant difference was found in the incidence of DVT between the heparin (+) and (−) periods [11.8% (11/93) vs. 11.1% (13/117)]. Sedation [odds ratio (OR)=3.78], physical comorbidities (OR=6.29) and a longer duration of restraint (OR=1.22) were associated with the incidence of DVT.ConclusionThe use of UFH was not associated with any reduction in the incidence of DVT in restrained psychiatric patients. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
