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小剂量肝素佐治小儿重症支气管肺炎的疗效观察
引用本文:曾雪飞,刘秀芳,李燕英,陈爱锋,何颖慧,邹莉,陈国华.小剂量肝素佐治小儿重症支气管肺炎的疗效观察[J].齐齐哈尔医学院学报,2009,30(8):913-913,917.
作者姓名:曾雪飞  刘秀芳  李燕英  陈爱锋  何颖慧  邹莉  陈国华
作者单位:广东省惠州市中心人民医院儿科,516001
基金项目:惠州市科技局科研项目 
摘    要:目的探讨小剂量肝素佐治小儿重症支气管肺炎的临床效果。方法68例重症支气管肺炎患儿被随机分为治疗组和对照组,两组患儿均给予吸氧、抗感染、强心及对症治疗,治疗组加用小剂量肝素,治疗后判断疗效,并测定血红细胞压积和血粘度。结果与对照组比较,治疗组治疗后的肺部哆音消失时间减少47.70%,气促恢复时间缩短27.95%,患者的总疗程缩短25.90%,治疗组的总有效率高于对照组,红细胞压积增加了57.69%,血粘度降低27.95%,在统计学上均有显著性差异(P〈0.05或P〈0.01)。结论小剂量肝素佐治小儿重症支气管肺炎可显著提高疗效。

关 键 词:小剂量肝素  小儿  重症  支气管肺炎

Treatment of infants serious bronchopneumonia with low dose of heparin
Institution:ZENG Xue - fei, et al. (Huizhou Muncipal Central Hospital, HuiZhou, Guangdong 516001 ,China)
Abstract:Objective To explore the clinical effects of low--dose heparin intervention on infants serious bronchopneumonia. Methods 68 cases of serious bronchopneumonia were randomly divided into therapeutic group and control group, two groups of infants were given oxygen, anti--infection, cardiac treatment and symptomatic treatment, therapeutic group was administered a low dose of heparin, after treatment to determine effect and determination of blood hematocrit and blood viscosity. Results Com- pared with the control group, therapeutic group after treatment of pulmonary got a reduction of disap- pearance time rate by 47.70%, shorten recovery time of hard breathe to 27.95 percent, shorten the overall course of treatment 25.90%, the total effective rates of therapeutic group was superior to the control group, red blood cell hematocrit increased 57.69 percent, blood viscosity reduced 27.95 percent, both had significant difference (P 〈 0.05 or P 〈 0.01). Conclusions Treatment of infants serious bronchopneumonia with low dose of heparin can significantly improve efficacy.
Keywords:Low-dose heparin Children Serious Bronchopneumonia
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