Effects of sodium fluoride on total serum protein levels and transaminase activity in rats. |
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| Authors: | D Qujeq B Laghaie A Gholipour N Solimani S Hassenzadeh |
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| Affiliation: | Department of Biochemistry and Biophysics, Babol University of Medical Sciences, Iran. dqujeq@hotmail.com |
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| Abstract: | Transaminase activity and serum total protein level were investigated in adult rats after oral treating with sodium fluoride at three doses, 10, 20 and 30 mg/kg daily for 90 days. After 90 days, the average total serum protein level of the rats in the treatment group decreased significantly compared with that in the control [1.9 +/- 0.1 (mean +/- S.D., n = 140) vs. 3.1 +/- 0.2] mg/dl, P< 0.05. Serum transaminase activity in the treatment group increased compared with that in the control [5.3 +/- 0.4 (mean +/- S.D., n = 140) vs. 3.2 +/- 0.3] micromol/min per ml, P < 0.05. |
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