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羊耳菊的化学成分研究(Ⅱ)
引用本文:郭启雷,杨峻山,刘建勋.羊耳菊的化学成分研究(Ⅱ)[J].中药材,2007,30(1):35-37.
作者姓名:郭启雷  杨峻山  刘建勋
作者单位:1. 中国医学科学院中国协和医科大学药用植物研究所,北京,100094;中国中医科学院西苑医院实验研究中心,北京,100091
2. 中国医学科学院中国协和医科大学药用植物研究所,北京,100094
3. 中国中医科学院西苑医院实验研究中心,北京,100091
摘    要:研究了菊科旋覆花属植物羊耳菊根的化学成分,从其甲醇提取物中分离得到东莨菪苷(Ⅰ),二十八烷酸(Ⅱ),三十三烷(Ⅲ)以及5个神经酰胺类化合物的混合物,分别为(2S,3S,4R,8E)-2-(2′R)-2′-羟基二十二烷酸酰胺]-十八烷-1,3,4-三醇(Ⅳ),(2S,3S,4R,8E)-2-(2′R)-2′-羟基二十三烷酸酰胺]-十八烷-1,3,4-三醇(Ⅴ),(2S,3S,4R,8E)-2-(2′R)-2′-羟基二十四烷酸酰胺]-十八烷-1,3,4-三醇(Ⅵ),(2S,3S,4R,8E)-2-(2′R)-2′羟基二十五烷酸酰胺]-十八烷-1,3,4-三醇(Ⅶ),(2S,3S,4R,8E)-2-(2′R)-2′-羟基二十六烷酸酰胺]-十八烷-1,3,4-三醇(Ⅷ)。以上化合物均为首次从该植物中分离得到。

关 键 词:羊耳菊  化学成分
文章编号:1001-4454(2007)01-0035-03
修稿时间:2006-07-05

Studies on the Chemical Constituents from Inula cappa(Ⅱ)
GUO Qi-lei,YANG Jun-shan,LIU Jian-xun.Studies on the Chemical Constituents from Inula cappa(Ⅱ)[J].Jorunal of Chinese Medicinal Materials,2007,30(1):35-37.
Authors:GUO Qi-lei  YANG Jun-shan  LIU Jian-xun
Institution:Institute of Medicinal Plant Development, Peking Union Medical College & Chinese Academy of Medical science, Beijing 100094, China. guo-ql@163.com
Abstract:OBJECTIVE: To study the chemical constituents of the root of Inula cappa. METHOD: The compounds were isolated and purified by recrystallization and chromatography with silica gel column and Sephadex LH-20 column. Their structures were identified by physico-chemical properties and spectral analysis. RESULTS: Seven compounds were isolated as scopolin (I), octacosanoic acid (II), tritriacontane (III), (2S,3S,4R,8E)-2-(2'R)-2'-hydroxydocosanosylamino]-octadecane-1,3,4-triol(IV),(2S,3S,4R,8E)-2-(2'R)-2'-hydroxytricosanosylamino]-octadecane-1,3,4-triol(V), (2S,3S,4R,8E)-2-(2'R)-2'-hydroxytetracosanosylamino]-octadecane-1,3,4-triol(VI), (2S,3S,4R,8E)-2-(2'R)-2'-hydroxypentacosanosylamino]-octadecane-1,3,4-triol(VIII), (2S,3S,4R,8E)-2-(2'R)-2'-hydroxyhexacosanosylamino]-octadecane-1,3,4-triol(VIII). CONCLUSION: All compounds were isolated from Inula cappa for the first time.
Keywords:Inula cappa  Chemical constituents
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