长期服用抗精神病药物患者胆结石患病情况及其影响因素

目的探讨长期服用抗精神病药物的精神疾病患者胆结石患病情况及其影响因素。方法对94例住院精神病患者（患者组）及154例健康体检者（对照组）进行B超检查,同时观察体重指数、血糖及病期等指标。结果胆结石检出率：患者组为25.5%（其中男23.72%,女28.57%）,对照组为6.49%（其中男6.89%,女5.56%）。患者组体重指数和血糖方面高于对照组,差异具有统计学意义。结论长期服用抗精神病药物的精神病患者胆结石发生率明显高于正常人群,其原因可能与服用抗精神病药物后患者活动减少,体重增加,糖、脂质代谢异常以及胆囊收缩功能下降等因素有关。

Prevalence of gallstones and correlation influence factors in psychiatric patients taking anti-psychosis continue

Objective To explore the prevalence of gallstones and correlation factors in psychiatric patients taking anti-psychosis continue.Methods 94 patients（patient group） and 154 healthy people（control group） were examined with B-ultrasonic,and their body mass index（BMI）,blood glucose and the course of disease were observed.Results The detection rate of gallstones in patient group was 25.5%（male 23.72%,female 28.57%）,while it was 6.49% in control group（male 6.89%,female 5.56%）,It was statistically significant that difference of BMI and the levels of between both groups（P0.01）.The levels of BMI and blood glucose in the psychiatric patients with gallstones was higher than the group without gallstones.Conclusion The incidence of gallstones in psychiatric patients is much higher than that in normal people,which may be related to less movement,weight gain,metabolism disorder of glucose and weak contractility of cholecyst after the taking anti-psychosis.