| 吉非替尼与培美曲塞治疗NSCLC脑转移的疗效比较 |
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| 引用本文： | 吴庭安. 吉非替尼与培美曲塞治疗NSCLC脑转移的疗效比较[J]. 中国航天工业医药, 2010, 0(6): 30-32 |
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| 作者姓名： | 吴庭安 |
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| 作者单位： | 广东省江门市中心医院肿瘤科,529000 |
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| 摘 要： | 目的探讨吉非替尼和培美曲塞治疗非小细胞肺癌脑转移的疗效。方法对2007年1月~2009年12月我院肿瘤内科收治的35例进行吉非替尼和培美曲塞治疗的非小细胞癌脑转移患者资料进行总结,分析其总有效率和不良反应。结果吉非替尼组RR（CR＋PR）率高于培美曲塞组,两组治疗不良反应无明显差异。结论吉非替尼对非小细胞肺癌脑转移治疗有较好效果,但是要注意其不良反应如皮疹、腹泻等的控制。
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| 关 键 词： | 吉非替尼 培美曲塞 非小细胞肺癌 脑转移 |
The efficacy of gefitinib compared with pemetrexed for NSCLC brain metastases |
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| Wu Tingan. The efficacy of gefitinib compared with pemetrexed for NSCLC brain metastases[J]. , 2010, 0(6): 30-32 |
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| Authors: | Wu Tingan |
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| Affiliation: | Wu Tingan.Oncology Department, Central Hospital of Jiangmen,Jiangmen 529000 |
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| Abstract: | Objective To evaluate gefitinib and pemetrexed treatment of non-small cell lung cancer with brain metastasis efficacy. Methods Jan 2007 to Dec 2009 admitted to our hospital oncology for 35 cases of gefitinib and pemetrexed treatment of non-small cell lung cancer patients with brain metastases to summarize, analyze its overall efficiency and adverse reaction. Results Gefitinib in the RR （CR＋PR） was higher than that pemetrexed group, two groups of treatment of adverse reactions was no significant difference. Conclusion Gefitinib for non-small cell lung cancer with brain metastasis treatment better results, but should pay attention to its adverse reactions such as rash and diarrhea control. |
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| Keywords: | Gefitinib Pemetrexed Non-small cell lung cancer Brain metastases |
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