Screening of Epstein—Barr Virus Early Antigen Expression Inducers from Chinese Medicinal Herbs and Plants |
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作者姓名: | ZENGY ZHONGJian-Ming 等 |
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作者单位: | [1]InstituteofVirology,ChineseAcademyofPreventiveMedicine,Beijing [2]NasopharyngealControlandTreatmentInsti,ChineseAcademyofPreventiveMedicine,Beijing |
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摘 要: | Ethern extracts of 1693 Chinese medicinal herbs and plants from 268 families were studied for the induction of Epstein-Barr viral(EVB)early antigen(EA)expression in the Raji cell line.Fifty-two from 18 families were found to have inducing activity.Twenty-five and seven of them were from Euphorbiaceae and Thymelaeaceae,respactively.Some of them,such as Croton tiglium,Euphorbia kansui,Daphne genkwa,Wikstroemia chamaedaphen,Wikstroemia indica,Prunus mandshurica Koehne and Achyranthes bidentata are commonly used drugs.The significance of these herbs in the activation of EBV in vivo and their relation to the development of nasopharyngeal carcinoma were discussed.
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关 键 词: | E-B病毒 早期抗原表达 中药材 中草药 诱发活性 筛选 |
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