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超敏C反应蛋白对慢性阻塞性肺疾病患者病情的评估价值
引用本文:赵宇,周秋玲,李莉.超敏C反应蛋白对慢性阻塞性肺疾病患者病情的评估价值[J].临床医药实践,2008(14):513-514.
作者姓名:赵宇  周秋玲  李莉
作者单位:深圳市第八人民医院深圳市宝安人民医院呼吸内科
摘    要:目的:比较慢性阻塞性肺疾病(COPD)患者不同病期(急性加重期和稳定期)的血清超敏C反应蛋白(hs-CRP)水平,分析其在COPD病情评估中的意义。方法:选择COPD患者40例,分别在急性加重期和稳定期测定血清hs-CRP、ESR、WBC水平。hs-CRP测定方法采用胶乳免疫增强比浊法。结果:COPD患者急性加重期血清hs-CRP水平较稳定期明显上升,差异有显著统计学意义(P<0.01)。WBC、ESR变化则较小。结论:hs-CRP可作为评估COPD病情的敏感指标。

关 键 词:慢性阻塞性肺疾病  超敏C反应蛋白  急性加重期  稳定期

Evaluative value of hs-CRP on the severity of condition in patients with chronic obstructive pulmonary disease
ZHAO Yu,Zhou Qiu-ling,LiLi.Evaluative value of hs-CRP on the severity of condition in patients with chronic obstructive pulmonary disease[J].Proceeding of Clinical Medicine,2008(14):513-514.
Authors:ZHAO Yu  Zhou Qiu-ling  LiLi
Institution:.Department of Respiratory Medicine Baoan People’s Hospital,Shenzhen Guangdong 518101,China
Abstract:Objective To compare the level of serum hs-CRP in patients with COPD in different conditions.Methods Fourty patients with COPD were selected.Serum hs-CRP(by latex—enhanced immunonephelometric assay),ESR and WBC levels were detected both in acute exacerbation phase and stable phase in 40 patients.Results Serum hs-CRP levels in acute exacerbation phase increase signif icantly than that in stable phase(P<0.01).The changes of WBC and ESR were small.Conclusion Serum hs-CRP can be used to evaluate the condition of COPD as a sensitive indicator.
Keywords:chronic obstructive pulmonary disease  high-sensitive C-reactive protein  acute exacerbation phase  stable phase  
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