血清指标与慢性肝炎病理关系分析

探讨血清指标与慢性肝炎病理分级、分期的关系。方法:对30例慢性肝炎患者的血清生化指标RBC、PLT、GGT、ALP、AST、HA、PⅢP、CⅣ、LN与病理分级、分期进行对比分析。结果:RBC,PLT,GGT,AST、ALP,CⅣ,LN与炎症程度有关。HA,PⅢP与炎症及纤维化程度有较好的相关性,HA判断肝纤维化准确性66.67％,特异性75.6％,敏感性65.38％。结论:血清生化指标与慢性肝炎病理分级、分期有明显的关系,对诊断肝纤维化具有较高的准确性和特异性。

Analysis of the Correlation between Serum Markers and Pathology of Chronic Hepatitis

To investigate the relationship between serum markers and the grades and stages of chronic hepatic pathology . Methods: A comparative analysis was carried out in 30 padents with chronic hepatitis by comparing their serum markers such as RBC,PLT,GGT,ALP,AST,HA,PIIIP,CIV,LN with the findings of liver biopsy. Results : RBC,PLT,GGT, AST, ALP,CIV, LN were related to the degree of inflammation. HA, PIIIP were obviously relevant to both inflammation and fibrosis. The accuracy, specificity and sensitivity of HA to judge liver fibrous were separately 66.67% , 75,6% and 65.38%. Conclusion: There is obvious correlation between serum boiologic chemistry markers and the pathologic grades and stages of chronic hepatitis , which had better accuracy and specificity to diagnose liver fibrosis.