| 迷走神经心脏效应的离子通道基础 |
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| 引用本文： | 骆海舰,张凤杰,司军强. 迷走神经心脏效应的离子通道基础[J]. 农垦医学, 2007, 29(4): 309-312 |
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| 作者姓名： | 骆海舰 张凤杰 司军强 |
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| 作者单位： | 石河子大学医学院新疆地方与民族高发病重点实验室-电生理研究室,新疆石河子,832002;石河子大学医学院新疆地方与民族高发病重点实验室-电生理研究室,新疆石河子,832002;石河子大学医学院新疆地方与民族高发病重点实验室-电生理研究室,新疆石河子,832002 |
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| 基金项目： | 石河子大学自然科学研究与发展基金 |
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| 摘 要： | 近年来自主神经与心律失常、血管迷走性晕厥(vasovagal syncope, VS)、心脏性猝死(sudden cardiac death, SCD)和离子通道病(ion channelopathy, ICP or ion channel disease ICD)等心血管疾病的关系越来越受到人们的重视.本文从离子通道和心脏M受体的角度对迷走神经的心脏效应予以回顾,这对于揭示迷走神经心脏效应的深层机制及深化对上述疾病的认识是有必要的.
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| 关 键 词： | 迷走神经 乙酰胆碱 M受体 离子通道 |
Ion Channels Related to Cardiac Effects of Vagus Nerve |
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| Luo HaiJian,Zhang FengJie,Si JunQiang. Ion Channels Related to Cardiac Effects of Vagus Nerve[J]. Agricultural Reclamation Medicine, 2007, 29(4): 309-312 |
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| Authors: | Luo HaiJian Zhang FengJie Si JunQiang |
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| Affiliation: | Division of Electrophysiology, Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Shihezi University School of medicine, Xinjiang, Shihezi, 832002 |
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| Abstract: | In recent years, the association between autonomic nervous system and some cardiovascular diseases, including arrhythmia, ion chaanelopathy, vasovagal syncope, sudden cardiac death hosbeen emphasized increasingly. The present article has revealed the progress in study of muscarinic acetylcholine receptors and relevant ion channels to influence of vagus nerve on the cardiac function from molecular biology, pharmacology, distribution and function areas. Based on them, we have reviewed the ionic mechanisms of some aspects of cardiac vagal effects ascensively which would help us to more deeply comprehend the essence of the above mentioned diseases. |
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| Keywords: | vagus nerve acetylcholine muscarinic receptors ion channel |
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