全身复合麻醉在动物实验中的应用研究

目的 研究动物实验中的最佳麻醉方法。方法 针对不同实验动物，选用不同药物，采取不同的麻醉方法，对实验动物进行复合麻醉，综合判断麻醉效果。结果 将盐酸氯胺酮、速眠新和安定三者以4：2：1（体积比）的比例混合进行静脉复合麻醉，麻醉效果最为理想；对犬、猫和猪，以静肌复合麻醉效果最为理想；抗胆碱药阿托品作为辅助麻醉药物，能有效地预防麻醉过深的发生。结论 对实验动物进行合理的复合麻醉能达到理想的麻醉效果。

Application of Systemic Combined Anesthesia in Animal Experiments

Objective To evaluate the optimal anesthesia in animal experiments. Methods Several animal species ware used in this study: mice, rats, guinea pigs, rabbits, dogs, cats, pigs and gouts. Combined anesthesia was tested on several animal species, in different ways and with different anesthetics, and the results were evaluated. Results The combination of ketamine hydrocholoride, sumianxin and diazepam in a ratio of 4:2:1 was found to be an optimal intravenous anesthetic agent. For canine, feline and swine, combined anesthesia of both intravenous and intramuscular was most satisfactory. Combined use of atropine, which is an anticholinergic agent, can effectively avoid overanesthesia. Conclusion Satisfactory results of anesthesia in experimental animals can be obtained with an appropriate combined anesthesia.