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安非拉酮应用于单纯性肥胖症84例
引用本文:席先成,周冰心,张怡泰,赵锦玲. 安非拉酮应用于单纯性肥胖症84例[J]. 中国新药与临床杂志, 1991, 0(6)
作者姓名:席先成  周冰心  张怡泰  赵锦玲
作者单位:中国人民解放军第88医院,山东潍坊制药二厂,潍坊医学院,青岛医学院 泰安 271000,潍坊 261021,潍坊 261021,青岛 266001
摘    要:安非拉酮化学名为二乙胺苯丙酮,为中枢性食欲抑制剂。据84例服25mg tid×2mo临床验证资料,本品治疗单纯性肥胖有效率为98%,治疗2mo平均降体重7.2±2.4kg,疗效高于对照组七消丸及文献报道的类似产品。本品对心、肝、肾及血象无不良反应。治疗期间注意低热量饮食以增加减肥效果。

关 键 词:安非拉酮  食欲抑制剂  肥胖

Amfepramone in 84 patients with simple obesity
XI Xian-Cheng,ZHOU Bing-Xin,ZHANG Yi-Tai,ZHAO Jin-Ling. Amfepramone in 84 patients with simple obesity[J]. Chinese Journal of New Drugs and Clinical Remedies, 1991, 0(6)
Authors:XI Xian-Cheng  ZHOU Bing-Xin  ZHANG Yi-Tai  ZHAO Jin-Ling
Abstract:Amfepramone, (diethylpropion) is a central anorectic drug applied for reducing body weight in patients with simple obesity. Eighty-four patients with obesity were treated with amfepramone 25 rng tid for 2 mo, the response rate was 98%, 7.2±2.4 kg of body weight were lost. It was effective for reducing body weight than that of control group given Qixiao Wan. It had no adverse effects to heart, liver, kidney and blood cells. In order to enhance the clinical effects, low calorie controlled diets in the course of treatment is suggested.
Keywords:amfepramone  appetite depressants  obesity  
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