贲门失弛缓症食管运动障碍治疗前后对比研究

目的 :探讨贲门失弛缓症患者行气囊扩张治疗前后食管运动障碍的变化。方法 :对 18例贲门失弛缓症患者采用气囊扩张治疗 ,并于治疗前和治疗后 48小时及治疗后 1个月分别进行食管测压 ,观察下食管括约肌的长度 (L ESL )、静息压力 (L ESP)、松弛压 (L ESRP)、松弛率 (L ES-PR)及食管体部运动障碍的变化。结果 :18例贲门失弛缓症患者治疗后 L ESP,L ESRP均显著降低 (P<0 .0 0 1) ,L ES-PR较治疗前显著提高 (P<0 .0 0 1) ,L ESL 治疗前后无差异 ,食管体部运动障碍治疗前后改善不明显。结论 :采用气囊扩张治疗贲门失弛缓症显效迅速 ,并能显著改善食管运动障碍

Comparative study on the change of esophageal motility in achalasia before and after treatment

Objective:It is to investigate the change of esophageal motility in achalasia before and after treatment with balloon dilation. Methods: Eighteen patients with achalasia were treated with balloon dilation. Esophageal motor function was inspected before treatment and after treatment for 48 hours and 1 month. LESL, LESP, LESRP, LES PR and the change of motor patterns of esophageal body were observed. Results: After treatment, LESP and LESRP lowered significantly ( P <0.001), and LES PR increased significantly ( P< 0.001). But there was no difference in LESL, and the improvement of motor patterns of esophageal body was not marked.Conclusion: The balloon dilation on achalasia takes effect speedily, and can significantly improve the esophageal motility.